A Black and White Response to the “Gray Zone” for Fractional Flow Reserve Measurements
نویسندگان
چکیده
منابع مشابه
A black and white response to the "gray zone" for fractional flow reserve measurements.
Petraco et al. (1) raise a universal issue that affects all clinical tests. Every binary cutoff produces cases just on either side of the threshold for whom a repeat measurement might alter the decision, no matter how accurate the test or how small its variability. By analogy to a Gaussian distribution of observations about the true value, the critical measure for any diagnostic test remains th...
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Pressure wire-based fractional flow reserve is considered the standard of reference for evaluation of the ischemic potential of coronary stenoses and the expected benefit from revascularization. Accordingly, its application in daily practice or for research purposes has to be as standardized as possible to avoid technical or operator-related artifacts in pressure recordings. This document propo...
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OBJECTIVES This study sought to assess the impact of a wide range of mean right atrial pressure (Pra) on fractional flow reserve (FFR) measurements. BACKGROUND FFR invasively assesses the ischemic potential of coronary stenoses. FFR is calculated as the ratio of mean distal coronary pressure (Pd) to mean aortic pressure (Pa) during maximal hyperemia. The Pra is considered to have little impac...
متن کاملLong-term outcome after deferral of revascularization in patients with intermediate coronary stenosis and gray-zone fractional flow reserve.
BACKGROUND A strategy of deferred percutaneous coronary intervention for coronary stenosis with fractional flow reserve (FFR) 0.75-0.80, termed the gray zone, remains a matter of debate. The aim of this study was to assess the safety of deferring revascularization for patients with FFR 0.75-0.80 compared with those with FFR >0.80. METHODS AND RESULTS We assessed 3-year clinical outcome in 150...
متن کاملDelineating the guide-wire flow obstruction effect in assessment of fractional flow reserve and coronary flow reserve measurements.
Hemodynamic analysis was conducted to determine uncertainty in clinical measurements of coronary flow reserve (CFR) and fractional flow reserve (FFR) over pathophysiological conditions in a patient group with coronary artery disease during angioplasty. The vasodilation-distal perfusion pressure (CFR-p(rh)) curve was obtained for 0.35- and 0.46-mm guide wires. Our hypothesis is that a guide wire...
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ژورنال
عنوان ژورنال: JACC: Cardiovascular Interventions
سال: 2014
ISSN: 1936-8798
DOI: 10.1016/j.jcin.2013.06.018